GcMAF


GcMAF - Your body´s own internal medicine

Your GcMAF empowers your body to cure itself. In a healthy person your own GcMAF has 11 actions discovered so far, including two on cells, three on the brain, and 6 on cancer. Amongst these it acts as a "director" of your immune system. But viruses and malignant cells like cancer send out an enzyme called Nagalase that prevents production of your GcMAF: that stops its 11 beneficial effects, and neutralises your immune system. So diseases become chronic, and cancer cells grow unchecked.

Gc-MAF is available in NZ from Registered Medical Practitioners.
For a list of NZ Doctors who treat with GcMAF go to our Doctors Page.

What is GcMAF?
GcMAF is a protein made by all healthy people.

Why do some people no longer make GcMAF?
Cancers and Viruses send out an enzyme called Nagalase that neutralises the bodies ability to make GcMAF. (without GcMAF our immune system goes to sleep)

What can we do if we no longer make GcMAF?
We make GcMAF outside the body and then administer it.

How does GcMAF Work with Cancer? Link to Supporting Abstract
  1. GcMAF activates white blood cells in our tissue, called macrophages, to attack and digest cancers.

  2. GcMAF directly inhibits cancer cell proliferation and metastatic potential.

  3. GcMAF directly turns cancer cells back into healthy cells (reverts phenotype).

  4. GcMAF directly inhibits cancer cell-induced angiogenesis (stops blood supply to tumours).

  5. GcMAF induces apoptosis (suicide of cancer cells).

  6. OA-GcMAF suppresses HER2 oncogene expression in human breast cancer. Link to Supporting Article

For cancer, follow the protocol. GcMAF Cancer Protocol

GcMAF and Nagalase

Some Published Scientific Articles Supporting GcMAF


  • 2015 Feb, OA-GcMAF counteracts the neuronal damage induced by oxaliplatin (chemotherapy).
    Link to Abstract

  • 2014 Oct 9, Glycosylated oleic acid/vitamin dbinding protein suppresses HER2 oncogene expression in human breast cancer.
    Link to Abstract    Download Full Article    Download Poster

  • 2014 Oct 8, Focussed transcranial ultrasounds: application to the delivery of glycosylated oleic acid/vitamin d-binding protein to brain tumours and metastases.
    Link to Abstract    Download Full Article    Download Poster

  • 2014 Oct 8, The effect of Gcmaf complexed with oleic acid on multiple myeloma cultures.
    Link to Abstract    Download Full Article

  • 2014 Oct 7, Clinical experience of immunotherapy based on oleic acid bound to glycosylated vitamin d-binding protein in localised and metastatic adenocarcinoma of the pancreas.
    Link to Abstract    Download Full Article    Download Poster

  • 2014 Sep 28, Clinical experience of renal carcinoma immunotherapy with oleic acid complexed with de-glycosylated vitamin d binding protein.
    Download Full Article

  • 2014 Sep 18-20, Gc-protein-derived Macrophage Activating Factor (GcMAF) induces ERBB2 shift in human breast cancer.
    Link to Abstract   

  • 2014 Sep 18-20, Intra-tumoural nitric oxide release by macrophages activated by Gc-protein-derived Macrophage Activating Factor (GcMAF).
    Here we demonstrate that intra-tumoural injection of OA-GcMAF leads NO synthesis and release inside the tumour.
    Link to Abstract   

  • 2014 May 28-31, Clinical experience of integrative immunotherapy centred on oleic acid complexed with deglycosylated vitamin D-binding protein.
    Download Full Article

  • 2014 May 28-31, Increased splenic blood flow following macrophage activation by oleic acid complexed with vitamin D-binding protein.
    Download Poster

  • 2014 May 27, Oleic Acid, deglycosylated vitamin D-binding protein, nitric oxide: a molecular triad made lethal to cancer.
    Link to Abstract    Download Full Article

  • 2014 Apr 17, The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages.
    Link to Abstract    Download Full Article

  • 2014 Mar 8, Clinical experience treating cancer with high dose OA-GcMAF and the approximate, average, decrease of tumor volume of 25% in a week.
    Link to Abstract    Download Full Article

  • 2013 Nov 6, The therapeutic effects of GcMAF in Chronic Fatigue Syndrome are confirmed here.
    Link to Abstract    Download Full Article

  • 2013, Newly described effects of GcMAF to treat neurodegenerative disorders from Parkinson’s and Alzheimer’s diseases to Myalgic Encephalomyelitis and Autism Spectrum Disorder.
    Link to Abstract    Download Full Article

  • 2013, Effects of GcMAF on Human Neuroblastoma cells and predicted molecular interaction with the vitamin D receptor.
    Download Poster

  • 2013 Aug, Effects of GcMAF on Human Breast Cancer and Neuroblastoma cells.
    Download Poster

  • 2013 Aug 22, Multifaceted immunotherapeutic effects of vitamin D-binding protein-derived macrophage activating factor (GcMAF) on human breast cancer and neuroblastoma cells.
    Link to Abstract   

  • 2013 Aug 20, Therapeutic effects of highly purified de-glycosylated GcMAF in the immunotherapy of patients with chronic diseases.
    Link to Abstract    Download Full Article

  • 2013 Jul 29, GcMAF decreases nagalase with associated improved clinical outcomes in advanced cancer patients.
    Link to Abstract     Download Full Article

  • 2013 July, GcMAF, Vitamin D and Oleic Acid induces human breast cancer cell apoptosis through stimulation of macrophages.
    Link to Abstract    Download Full Article

  • 2013 Jun 20-21, The immune stimulant properties of GcMAF on Gynaecological Cancers.
    Download Poster

  • 2013 Jun 20-21, Molecular interaction of GcMAF with vitamin D receptor in Endometrial Cancer.
    Download Poster

  • 2013 Jan 31, Multifaceted immunotherapeutic effects of GcMAF on Human Breast Cancer cells.
    Download Poster

  • 2012 Dec, 40 cases of Autism improved with GcMAF.
    Link to Abstract    Download Full Article

  • 2011, Macrophages of the mucosa-associated lymphoid tissue (MALT) as key elements of the immune response to vitamin d binding protein-macrophage activating factor. Demonstrates that OA-GcMAF Probiotic (MAF 314) substantially increases CD4 count in HIV/AIDS patients.
    Link to Abstract    Download Full Article

  • 2010, GcMAF directly inhibits prostate cancer cells.
    Link to Abstract    Download Full Article


Viruses or Parasites are often a Cause of Cancer


Accepted Causes of Cancer
Associated Causes of Cancer


For more information on GcMAF, go to the manufacturer's webpage www.GcMAF.eu